Damage Control Protocol (Recomp Performance Nutrition )

[Devil]

RPN DCP (Damage Control Protocol) 180 tabs

DCP is an effective combination of TetradecylThioacetic Acid (250mg), Salvia Miltiorrhiza Extract (standardized for 40% Mixed Tanshinones) (250mg), Propionyl-L-Carnitine (300mg), Potassium Pyruvate (300mg), and Raspberry Ketones (100mg). You may have seen some of these ingredients in other products, but lets look at why we chose them specifically to work in concert to help you become the lean, mean, muscle building machine you want to be.

The center ingredient in which our product is based off of is of TetradecylThioacetic Acid (TTA). TTA is a 3-thia fatty acid which increases mitochondrial activity, which in itself provides numerous benefits. Insulin resistance is strongly linked to the reduction of glucose oxidation in mitochondria and a subsequent build up of glycolysis byproducts. Adipocytes also contribute hormones when fat is stored in them, so, the more fat you are carrying, the more inhibition of mitochondrial function you have (1). Mitochondria proteins function mainly to produce ATP, enhancing their function will, in short, burn more fuel. TTA enhances mitochondrial oxidative capacity and reduces free fatty acid and triglyceride levels as described below.

The peroxisome proliferator-activated receptors (PPARs) are transcription factors regulated by fatty acid derivatives, among others. These receptors are intimately involved in glucose regulation, cellular proliferation and differentiation, and most important to us, fat metabolism. There are at present three types of PPARs: alpha, gamma, and delta. The liver is the main site where fatty acids are stored or burned for energy, depending on calorie intake.

When fasting, fuel sources switch from carbohydrates and fats to mainly fats, and fatty acids are released from adipocytes. In the liver, they are either reesterified to triglycerides and form very low-density lipoproteins (VLDL), which then go on to restore in adipocytes or go to cardiac and skeletal muscle for energy. They can also be broken down through beta-oxidation to form ketones. PPAR-alpha mediates the genes controlling fatty acid uptake, beta-oxidation, and gamma-oxidation, which are upregulated when in a fasted state. TTA is a PPARalpha agonist, meaning it activates these receptors. Thus, you experience the same benefits even if you are in a fed state (9,15-18). PPAR-alpha also down-regulates apolipoprotein C-III which inhibits triglyceride hydrolysis, further enhancing lipid oxidation (2).

TTA also increases the activity of enzymes of the carnitine palmitoyltransferase (CPT) sytem (9), which shuttles the newly freed up fatty acids into mitochondria to be burned for fuel (10). This system is highly underestimated in a fat loss quest, and it's activity is depressed with increased fat. Propionyl-LCarnitine (PLCAR) was added to further stimulate the CPT system (11), and is converted into propionylcoenzyme A and free carnitine (12). PLCAR has also been suspected to scavenge free radicals, as well as protect DNA from UV damage (12).

Pyruvate is involved in another complex system called the Pyruvate Dehydrogenase Complex (PDC), which interacts with the CPT system (13). Pyruvate is a Krebs Cycle intermediate, which is rate controlled by the amount of acetyl-CoA that enters the cycle, one of the conversions from pyruvate (13). For simplicity's sake, the result is an ATP/energy enhancement from the mitochondria and an increase in fuel consumption. The electrolyte potassium form was added to attenuate cramping issues observed from previous TTA products.

Raspberry Ketones (RK) add the finishing touch to DCP. RK is similar in structure to capsaicin and synephrine, and also has been shown to modulate fat metabolism. RK stimulates the release of norepinephrine (NE), a catecholamine with many functions. Most importantly to us is its role in the sympathetic nervous system. NE, having a great affinity on beta and alpha-1 adrenoreceptors in the body, activates lipolysis that normally only occurs during exercise or other intensive activity. This results in an increase of free fatty acids which will be burned via methods described above (14).

As you can see, DCP attacks fat from many angles. It can be especially effective when bulking to prevent fat storage and also has appetite suppressive properties in some users, or used in a cut to potentiate the body's fasting enzymatic response. Take control of your body with Damage Control Protocol!


Serving Size: 2 Tablets
Servings Per Container 90

Amount Per Serving % DV

Tetradecylthioacetic Acid 250mg**
Salvia Miltiorrhiza Extract (Standardized For 40% Mixed Tanshinones) 250mg**
Propionyl-L-Carnitine 300mg**
Potassium Pyruvate 300mg**
Raspberry Ketones 100mg**

** Daily Value not established

Other Ingredients: Gelatin(Capsule), Microcrystalline Cellulose

Directions: Take 2 tablets of DCP 3 times daily as needed or directed by your physician.

A suggested protocol to start out:

2 caps 30min before breakfast
2 caps 30min before lunch
2 caps 30min pre-workout (or dinner)

Dosage and timing can be experimented with.

υπαρχουν feedback για αυτο το προιον?
πως το βλεπετε?
υπαρχει κανει που εχει χρησιμοποιησει ΤΤΑ?

[mantus3]

εν τελοι τι υποτηθετε οτι κανει... με μπερδεψε...

[Eddie]

Devil,πες και κανα δυο λογια στα Ελληνικα για να βγει το νοημα,πολλοι δε ξερουν αγγλικα.

[primordial]

Αν δεν κάνω λάθος, πρέπει να είναι κάποιο είδους λιποδιαλύτης - carb blocker...????
Πρώτη φορά το βλέπω το συγκεκριμένο....... Κάποια γνώμη...???

[Machiavelli]

Αγαπημένο non-stimulant. Γενικά τα 2 προϊόντα με tta που έχω δοκιμάσει (αυτό και meltdown) είναι φοβερά. Για το συγκεκριμένο, χρησιμοποιώντας το μόνο του το μόνο που είδα ήταν αρκετά καλή πτώση λίπους (στον καθρέφτη πάντα) και ελαφρά θερμογένεση, χωρίς παρενέργειες. Το έχω stackάρει και με το scorch (που ήδη εκτιμούσα), καλύτερα αποτελέσματα αλλά με κάποιες ανησυχίες μέσα στον κύκλο.

[flowin_through]

Για ορμονικο ειναι το Mitotropin, για μη ορμονικο το Oxyelite και για μη διεγερτικο αυτο. Εν ολιγοις τα κορυφαια ανα ειδος. Αυτα λενε τα feedback. Δεν το εχω παρει ακομα αλλα το TTA εχει πολυ ελπιδοφορες ερευνες και ντορο. Αν προκειται για stack, υπαρχει και σκετο TTA απο SNS.

Maki δε σε πιστευουμε. Αφου δε δοκιμασες Swagger δεν εχεις κανει τιποτα.

[Devil]

παιδια δεν ξερω πολλα πραγματα σε σχεση με το ΤΤΑ
τις τελευταιες μερες το ψαχνω το θεμα και φαινετε ιδιαιτερα ενδιαφερον

το προιον ειναι κατι μεταξυ fat-burner (no stim) και damage control σε περιοδους οπου δεν κανεις διατροφη για να μην παρεις πολυ λιπος.

αν βρω περισοτερες info θα ποσταρω
το μονο που γνωριζω ειναι οτι δρα περιπου σαν την σεσαμινα σαν αγωνιστης των PPAR.

απλα ψαχνω feedback μεχρι στιγμης

[Devil]

TetradecylThioacetic Acid (TTA), a non beta-oxidizable fatty acid analog, has been shown to activate all three of the PPAR receptors in rats, in the ranking order of Alpha > Beta/Delta > Gamma (Madsen et al. 2002).

TTA has been shown to increase insulin sensitivity by increasing hepatic fat oxidation and ketogenesis while draining fatty acids from the blood and extrahepatic tissues. This drainage of fatty acids by the liver increases the ability of adipocytes and skeletal muscle in uptake glucose (Grav et al. 2003).

TTA has been shown to cause mitochondrial and peroxisomal proliferation in rats (Kryvi et al. 1990), leading to increased beta-oxidation of fatty acids in the liver, along with increasing uncoupling protein-2 (UCP-2) expression (Grav et al. 2003). UCP-2, and UCP-3, is involved in preventing the accumulation of oxygen-specific free radicals and in regulating lipogenesis and ketogenesis.

UCP-2 is found throughout the body (Grav et al. 2003). These three adaptations, increased mitochondria, peroxisomes, and UCP-2 concentrations, all aid in increasing insulin sensitivity and reducing adiposity.


το πηρα απο ενα αρθρο στο bb.com
με λιγα λογια το ΤΤΑ λειτουργει σαν αγωνιστης των ΡΡΑR (νομιζω κυριος των αλφα) και ετσι εχουμε καλητερη ''αισθηση'' της
ινσουλινης και αυξηση της καυσης των λιπων.

[Devil]

Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation.

Løvås K, Røst TH, Skorve J, Ulvik RJ, Gudbrandsen OA, Bohov P, Wensaas AJ, Rustan AC, Berge RK, Husebye ES.

Institute of Medicine, University of Bergen, Bergen, Norway. kristian.lovas@helse-bergen.no
Abstract

AIM: We previously demonstrated that a modified fatty acid, tetradecylthioacetic acid (TTA), improves transport and utilization of lipids and increases mitochondrial fatty acid oxidation in animal and cell studies. We conducted an exploratory study of safety and effects of this novel drug in patients with type 2 diabetes mellitus and investigated the mechanism of action in human cell lines. METHODS: Sixteen male patients with type 2 diabetes mellitus received 1 g TTA daily for 28 days in an open-labelled study, with measurement of parameters of lipid metabolism, glucose metabolism and safety (ClinicalTrials.gov NCT00605787). The mechanism of action was further investigated in a human liver cell line (HepG2) and in cultured human skeletal muscle cells (myotubes). RESULTS: Mean LDL cholesterol level declined from 4.2 to 3.7 mmol/l (p < 0.001), accompanied by increased levels of the HDL apolipoproteins A1 and A2, and a decline in LDL/HDL ratio from 4.00 to 3.66 (p = 0.008 ). Total fatty acid levels declined, especially the fraction of the polyunsaturated n-3 fatty acids docosahexaenoic acid (-13%, p = 0.002) and eicosapentaenoic acid (-10%, p = 0.07). Glucose metabolism was not altered and the drug was well tolerated. In cultured liver cells, TTA acted as a pan-PPAR agonist with predominant PPAR-alpha and PPAR-delta activation at low TTA concentrations. In myotubes, TTA and a PPAR-delta agonist, but not the PPAR-alpha or PPAR-gamma agonists, increased the fatty acid oxidation. CONCLUSIONS: We demonstrate for the first time that TTA attenuates dyslipidaemia in patients with type 2 diabetes mellitus. These effects may occur through mechanisms involving PPAR-alpha and PPAR-delta activation, resulting in increased mitochondrial fatty acid oxidation.

**** Κανε μια μικρη περίληψη στα Ελληνικα.Mods Team ****

απο google

Έχουμε αποδείξει για πρώτη φορά ότι το TTA μειωνει την δυσλιπιδαιμίας σε ασθενείς με σακχαρώδη διαβήτη τύπου 2. Αυτά τα αποτελέσματα μπορούν να προκύψουν μέσω των μηχανισμών που αφορούν την ενεργοποίηση των PPAR-άλφα και PPAR-delta , με αποτέλεσμα την αύξηση της οξείδωση των λιπαρών οξέων στα μιτοχόνδρια.

***Τα μεταφραστικα του google δεν βγαζουν νόημα.Mods Team ***

[eas2000]

Πολύ άκυρη ουσία φαινεται, προσωπικά ως προς την ασφάλειά της με φοβίζει

[Devil]

τσεκαρε την ερευνα αποπανω, φαινετε οκ

λειτουργει περιπου σαν την σεσαμινα και το CLA

[panzor]

και που βρίσκουμε τέτια συμπληρώματα? έχει κανένας από τους χορηγούς?
αφού δεν είναι ορμονικό ούτε θερμογενετικό σημαίνει οτι μπορείς να το στακάρεις με θερμογενετικό πχ?

[Machiavelli]

Το scorch που ανέφερα πιο πάνω ότι το stackαρα θερμογενετικό είναι.

[Bane]

Προσωπικά το ΤΤΑ δεν το έχω ιδιαίτερα σε εκτίμηση πάντως το συγκεκριμένο προιόν πέρνει πολύ καλές κριτικές έξω

[Devil]

Βane γιατι αυτο?

σε σχεση με την sesamin πιστευεις οτι ειναι καλητερο?

κατι αλλο σε non-stimulant?